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The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cells

Retinoic acids and their derivatives potentiate anti-cancer effects in breast cancer cells. The aberrant expression of telomerase is critical to the continued proliferation of most cancer cells. Thus, telomerase is an attractive target for chemo-prevention and treatment of breast cancer. 9cUAB30 is...

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Autors principals: HANSEN, NATHAN J., WYLIE, REBECCA C., PHIPPS, SHARLA M.O., LOVE, WILLIAM K., ANDREWS, LUCY G., TOLLEFSBOL, TRYGVE O.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435481/
https://ncbi.nlm.nih.gov/pubmed/17273765
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