Potent T cell agonism mediated by a very rapid TCR/pMHC interaction

The interaction between T cell receptors (TCR) and peptide-major histocompatibility complex (pMHC) antigens can lead to varying degrees of agonism (T cell activation), or antagonism. The P14 TCR recognises the lymphocytic choriomeningitis virus (LCMV)-derived peptide, gp33 residues 33–41 (KAVYNFATC)...

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Bibliografiske detaljer
Main Authors: Boulter, Jonathan M, Schmitz, Nicole, Sewell, Andrew K, Godkin, Andrew J, Bachmann, Martin F, Gallimore, Awen M
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag GmbH 2007
Fag:
Molecular Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435421/
https://ncbi.nlm.nih.gov/pubmed/17295390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200636743
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