The B Cell Antigen Receptor and Overexpression of MYC Can Cooperate in the Genesis of B Cell Lymphomas

A variety of circumstantial evidence from humans has implicated the B cell antigen receptor (BCR) in the genesis of B cell lymphomas. We generated mouse models designed to test this possibility directly, and we found that both the constitutive and antigen-stimulated state of a clonal BCR affected th...

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Bibliografske podrobnosti
Main Authors: Refaeli, Yosef, Young, Ryan M, Turner, Brian C, Duda, Jennifer, Field, Kenneth A, Bishop, J. Michael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435152/
https://ncbi.nlm.nih.gov/pubmed/18578569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060152
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