Insulin depletion leads to adipose-specific cell death in obese but not lean mice
Mutation of the obese gene produces obesity, hyperinsulinemia, and compensatory “overexpression” of the defective gene. As insulin activates obese gene expression, it seemed possible that hyperinsulinemia might be responsible for overexpression of the gene. To address this question we rapidly neutra...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14168 |
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