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Insulin depletion leads to adipose-specific cell death in obese but not lean mice

Mutation of the obese gene produces obesity, hyperinsulinemia, and compensatory “overexpression” of the defective gene. As insulin activates obese gene expression, it seemed possible that hyperinsulinemia might be responsible for overexpression of the gene. To address this question we rapidly neutra...

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Bibliográfalaš dieđut
Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Loftus, Thomas M., Kuhajda, Francis P., Lane, M. Daniel
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 1998
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24345/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14168
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