Insulin depletion leads to adipose-specific cell death in obese but not lean mice
Mutation of the obese gene produces obesity, hyperinsulinemia, and compensatory “overexpression” of the defective gene. As insulin activates obese gene expression, it seemed possible that hyperinsulinemia might be responsible for overexpression of the gene. To address this question we rapidly neutra...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24345/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14168 |
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