Stretched and overwound DNA forms a Pauling-like structure with exposed bases
We investigate structural transitions within a single stretched and supercoiled DNA molecule. With negative supercoiling, for a stretching force >0.3 pN, we observe the coexistence of B-DNA and denatured DNA from σ ≈ −0.015 down to σ = −1. Surprisingly, for positively supercoiled DNA (σ > +0.037) st...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14152 |
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