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Stretched and overwound DNA forms a Pauling-like structure with exposed bases

We investigate structural transitions within a single stretched and supercoiled DNA molecule. With negative supercoiling, for a stretching force >0.3 pN, we observe the coexistence of B-DNA and denatured DNA from σ ≈ −0.015 down to σ = −1. Surprisingly, for positively supercoiled DNA (σ > +0.0...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Allemand, J. F., Bensimon, D., Lavery, R., Croquette, V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24342/
https://ncbi.nlm.nih.gov/pubmed/9826669
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