A transient expansion of the native state precedes aggregation of recombinant human interferon-γ
Aggregation of proteins, even under conditions favoring the native state, is a ubiquitous problem in biotechnology and biomedical engineering. Providing a mechanistic basis for the pathways that lead to aggregation should allow development of rational approaches for its prevention. We have chosen re...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14142 |
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