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The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency

Activation of gene transcription in eukaryotes requires the cooperative assembly of an initiation complex containing many protein subunits. The necessity that these components contact each other and the promoter/enhancer in defined ways suggests that their spatial arrangement might influence the act...

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Detalhes bibliográficos
Main Authors: Chytil, Milan, Peterson, Blake R., Erlanson, Daniel A., Verdine, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24329/
https://ncbi.nlm.nih.gov/pubmed/9826656
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