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The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency

Activation of gene transcription in eukaryotes requires the cooperative assembly of an initiation complex containing many protein subunits. The necessity that these components contact each other and the promoter/enhancer in defined ways suggests that their spatial arrangement might influence the act...

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Bibliografiske detaljer
Main Authors: Chytil, Milan, Peterson, Blake R., Erlanson, Daniel A., Verdine, Gregory L.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24329/
https://ncbi.nlm.nih.gov/pubmed/9826656
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