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In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor

The nicotinic acetylcholine receptor (AChR) controls signal transmission between cells in the nervous system. Abused drugs such as cocaine inhibit this receptor. Transient kinetic investigations indicate that inhibitors decrease the channel-opening equilibrium constant [Hess, G. P. & Grewer, C. (199...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ulrich, Henning, Ippolito, Joseph E., Pagán, Oné R., Eterovic, Vesna A., Hann, Richard M., Shi, Hua, Lis, John T., Eldefrawi, Mohyee E., Hess, George P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24324/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14051
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