In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor
The nicotinic acetylcholine receptor (AChR) controls signal transmission between cells in the nervous system. Abused drugs such as cocaine inhibit this receptor. Transient kinetic investigations indicate that inhibitors decrease the channel-opening equilibrium constant [Hess, G. P. & Grewer, C. (199...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14051 |
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