Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion

In the present study, we tested the hypothesis that a mild cerebral tissue injury promotes subsequent glioma invasion via activation of the ADAM17-EGFR-PI3K-Akt pathway. Mild injury was induced by Photodynamic therapy (PDT), which employs tissue-penetrating laser light exposure following systemic ad...

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Xuguang, Jiang, Feng, Katakowski, Mark, Zhang, Xuepeng, Jiang, Hao, Zhang, Zheng Gang, Chopp, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432085/
https://ncbi.nlm.nih.gov/pubmed/18358600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.02.023
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