Human Neutrophils Convert the Sebum-derived Polyunsaturated Fatty Acid Sebaleic Acid to a Potent Granulocyte Chemoattractant

Sebaleic acid (5,8-octadecadienoic acid) is the major polyunsaturated fatty acid in human sebum and skin surface lipids. The objective of the present study was to investigate the metabolism of this fatty acid by human neutrophils and to determine whether its metabolites are biologically active. Neut...

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Detalhes bibliográficos
Main Authors: Cossette, Chantal, Patel, Pranav, Anumolu, Jaganmohan R., Sivendran, Sashikala, Lee, Gue Jae, Gravel, Sylvie, Graham, François D., Lesimple, Alain, Mamer, Orval A., Rokach, Joshua, Powell, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431088/
https://ncbi.nlm.nih.gov/pubmed/18287092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709531200
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