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5-oxo-15-HETE: Total Synthesis and Bioactivity
The first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE 4 was accomplished. The synthetic material was evaluated with calcium mobilization assay and compared with 5-oxo-ETE the natural ligand for the OXE receptor.
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052199/ https://ncbi.nlm.nih.gov/pubmed/21316960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.01.032 |
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