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5-oxo-15-HETE: Total Synthesis and Bioactivity

The first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE 4 was accomplished. The synthetic material was evaluated with calcium mobilization assay and compared with 5-oxo-ETE the natural ligand for the OXE receptor.

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Autors principals: Patel, Pranav, Anumolu, Jaganmohan R., Powell, William S., Rokach, Joshua
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052199/
https://ncbi.nlm.nih.gov/pubmed/21316960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.01.032
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