Llwytho...

C(20)-trifluoro-5-oxo-ETE: A metabolically stable 5-oxo-ETE derivative

The total synthesis of C(20)-trifluoro-6(E),8(Z),11(Z),14(Z) 5-oxo-ETE is reported. This compound was designed as an ω-oxidation-resistant analog of 5-oxo-ETE that would be resistant to metabolism. The trifluoro derivative of 5-oxo-ETE stimulated calcium mobilization in neutrophils and desensitized...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Patel, Pranav, Gore, Vivek, Powell, William S., Rokach, Joshua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062511/
https://ncbi.nlm.nih.gov/pubmed/21377873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.02.021
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!