ロード中...
Adaptor Protein Sorting Nexin 17 Regulates Amyloid Precursor Protein Trafficking and Processing in the Early Endosomes
Accumulation of extracellular amyloid β peptide (Aβ), generated from amyloid precursor protein (APP) processing by β- and γ-secretases, is toxic to neurons and is central to the pathogenesis of Alzheimer disease. Production of Aβ from APP is greatly affected by the subcellular localization and traff...
保存先:
主要な著者: | , , , , , , , |
---|---|
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
American Society for Biochemistry and Molecular Biology
2008
|
主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431074/ https://ncbi.nlm.nih.gov/pubmed/18276590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800642200 |
タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|