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A Novel Endogenous Human CaMKII Inhibitory Protein Suppresses Tumor Growth by Inducing Cell Cycle Arrest via p27 Stabilization

Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates numerous physiological functions. Inhibition of CaMKII activity, mostly by synthetic reagents, has been proved to suppress cell growth in many cases. So far there are no reports about the physiological functions and underlying mechani...

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מידע ביבליוגרפי
Main Authors: Wang, Chunmei, Li, Nan, Liu, Xingguang, Zheng, Yuanyuan, Cao, Xuetao
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431061/
https://ncbi.nlm.nih.gov/pubmed/18305109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800436200
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