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Neph1, a Component of the Kidney Slit Diaphragm, Is Tyrosine-phosphorylated by the Src Family Tyrosine Kinase and Modulates Intracellular Signaling by Binding to Grb2

There are several lines of evidence that the podocyte slit diaphragm (SD), which serves as a structural framework for the filtration barrier in kidney glomerulus, also plays an essential role as a signaling platform. Several SD components including nephrin and TRPC6 are known to be phosphorylated by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harita, Yutaka, Kurihara, Hidetake, Kosako, Hidetaka, Tezuka, Tohru, Sekine, Takashi, Igarashi, Takashi, Hattori, Seisuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431037/
https://ncbi.nlm.nih.gov/pubmed/18258597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707247200
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