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VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult

BACKGROUND: Excitotoxic brain insult is associated with extensive neuronal damage but could also cause inflammatory reactivity and vascular remodeling. The effects of the vascular endothelial growth factor (VEGF) inhibitor, Cyclo-VEGI on expression of VEGF, microgliosis and astrogliosis, blood-brain...

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Bibliografski detalji
Glavni autori: Ryu, Jae K, McLarnon, James G
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430697/
https://ncbi.nlm.nih.gov/pubmed/18492281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-18
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