Dystrophin deficient cardiomyopathy in mouse: Expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart

Duchenne muscular dystrophy (DMD; dystrophin-deficiency) causes dilated cardiomyopathy in the second decade of life in affected males. We studied the dystrophin-deficient mouse heart (mdx) using high frequency echocardiography, histomorphometry, and gene expression profiling. Heart dysfunction was p...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Spurney, Christopher F., Knoblach, Susan, Pistilli, Emidio E., Nagaraju, Kanneboyina, Martin, Gerard R., Hoffman, Eric P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430663/
https://ncbi.nlm.nih.gov/pubmed/18440230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2008.03.008
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares