טוען...
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
Cells respond to DNA double-strand breaks (DSBs) by recruiting factors such as the DNA-damage mediator protein MDC1, p53-binding protein 1 (53BP1) and the breast cancer susceptibility protein BRCA1 to sites of damaged DNA. Here, we reveal that the ubiquitin ligase RNF8 mediates ubiquitin conjugation...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430610/ https://ncbi.nlm.nih.gov/pubmed/18006705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1150034 |
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