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Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice

BACKGROUND: The rate at which a stretch of DNA mutates is determined by the cellular systems for DNA replication and repair, and by the nucleotide sequence of the stretch itself. One sequence feature with a particularly strong influence on the mutation rate are nucleotide repeats. Some microbial pat...

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Autors principals: Wanner, Roger M, Güthlein, Carolin, Springer, Burkhard, Böttger, Erik C, Ackermann, Martin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430213/
https://ncbi.nlm.nih.gov/pubmed/18507851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-249
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