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Important Role for Mycobacterium tuberculosis UvrD1 in Pathogenesis and Persistence apart from Its Function in Nucleotide Excision Repair

Mycobacterium tuberculosis survives and replicates in macrophages, where it is exposed to reactive oxygen and nitrogen species that damage DNA. In this study, we investigated the roles of UvrA and UvrD1, thought to be parts of the nucleotide excision repair pathway of M. tuberculosis. Strains in whi...

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Detalhes bibliográficos
Main Authors: Houghton, Joanna, Townsend, Carolin, Williams, Alan R., Rodgers, Angela, Rand, Lucinda, Walker, K. Barry, Böttger, Erik C., Springer, Burkhard, Davis, Elaine O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370636/
https://ncbi.nlm.nih.gov/pubmed/22467787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06654-11
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