UvrD2 Is Essential in Mycobacterium tuberculosis, but Its Helicase Activity Is Not Required

UvrD is an SF1 family helicase involved in DNA repair that is widely conserved in bacteria. Mycobacterium tuberculosishas two annotated UvrD homologues; here we investigate the role of UvrD2. The uvrD2gene at its native locus could be knocked out only in the presence of a second copy of the gene, de...

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Detaylı Bibliyografya
Asıl Yazarlar: Williams, Alan, Güthlein, Carolin, Beresford, Nicola, Böttger, Erik C., Springer, Burkhard, Davis, Elaine O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Molecular Biology of Pathogens
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165537/
https://ncbi.nlm.nih.gov/pubmed/21725019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00302-11
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