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Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis

OBJECTIVE: Osteoarthritis (OA) is associated with increased levels of reactive nitrogen and oxygen species and pro-inflammatory cytokines, such as interleukin-1 (IL-1). Nitric oxide (NO) can mediate a number of the catabolic effects of IL-1 in articular cartilage. The aims of this study were to dete...

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Bibliografske podrobnosti
Main Authors: Davies, Catrin M., Guilak, Farshid, Weinberg, J. Brice, Fermor, Beverley
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430155/
https://ncbi.nlm.nih.gov/pubmed/17945515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2007.09.012
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