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A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

Laron syndrome [growth hormone (GH) insensitivity syndrome] is a hereditary dwarfism resulting from defects in the GH receptor (GHR) gene. GHR deficiency has not been reported in mammals other than humans. Many aspects of GHR dysfunction remain unknown because of ethical and practical limitations in...

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書誌詳細
主要な著者: Zhou, Yihua, Xu, Bixiong C., Maheshwari, Hiralal G., He, Li, Reed, Michael, Lozykowski, Maria, Okada, Shigeru, Cataldo, Lori, Coschigamo, Karen, Wagner, Thomas E., Baumann, Gerhard, Kopchick, John J.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC24289/
https://ncbi.nlm.nih.gov/pubmed/9371826
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