A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

Laron syndrome [growth hormone (GH) insensitivity syndrome] is a hereditary dwarfism resulting from defects in the GH receptor (GHR) gene. GHR deficiency has not been reported in mammals other than humans. Many aspects of GHR dysfunction remain unknown because of ethical and practical limitations in...

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Detalhes bibliográficos
Main Authors: Zhou, Yihua, Xu, Bixiong C., Maheshwari, Hiralal G., He, Li, Reed, Michael, Lozykowski, Maria, Okada, Shigeru, Cataldo, Lori, Coschigamo, Karen, Wagner, Thomas E., Baumann, Gerhard, Kopchick, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24289/
https://ncbi.nlm.nih.gov/pubmed/9371826
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