Phosphatidic acid mediates demyelination in Lpin1 mutant mice

Lipids play crucial roles in many aspects of glial cell biology, affecting processes ranging from myelin membrane biosynthesis to axo-glial interactions. In order to study the role of lipid metabolism in myelinating glial cells, we specifically deleted in Schwann cells the Lpin1 gene, which encodes...

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Hlavní autoři: Nadra, Karim, de Preux Charles, Anne-Sophie, Médard, Jean-Jacques, Hendriks, William T., Han, Gil-Soo, Grès, Sandra, Carman, George M., Saulnier-Blache, Jean-Sébastien, Verheijen, Mark H.G., Chrast, Roman
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428062/
https://ncbi.nlm.nih.gov/pubmed/18559480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1638008
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