Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis

The Drosophila let-7-Complex (let-7-C) is a polycistronic locus encoding three ancient microRNAs: let-7, miR-100, and fly lin-4 (miR-125). We find that the let-7-C locus is principally expressed in the pupal and adult neuromusculature. let-7-C knockout flies appear normal externally but display defe...

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Bibliografiske detaljer
Main Authors: Sokol, Nicholas S., Xu, Peizhang, Jan, Yuh-Nung, Ambros, Victor
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2008
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428057/
https://ncbi.nlm.nih.gov/pubmed/18559475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1671708
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