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Relationships between the structure of organophosphorus compounds and their activity as acetylcholinesterase inhibitors
This paper discusses the relation between chemical structure and inactivation of the enzyme acetylcholinesterase (AChE) by organophosphorus esters, in terms of reactivity and steric effects. The discussion is centered in organophosphorus esters of the type (R) (R′) P(O) X, where X is a readily displ...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2428053/ https://ncbi.nlm.nih.gov/pubmed/5315349 |
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