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Relationships between the structure of organophosphorus compounds and their activity as acetylcholinesterase inhibitors

This paper discusses the relation between chemical structure and inactivation of the enzyme acetylcholinesterase (AChE) by organophosphorus esters, in terms of reactivity and steric effects. The discussion is centered in organophosphorus esters of the type (R) (R′) P(O) X, where X is a readily displ...

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Bibliografiske detaljer
Hovedforfatter: Fukuto, T. R.
Format: Artigo
Sprog:Inglês
Udgivet: 1971
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2428053/
https://ncbi.nlm.nih.gov/pubmed/5315349
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