T-cell Development and Function Are Modulated by Dual Specificity Phosphatase DUSP5

Interleukin-2 (IL-2) is a pleiotropic cytokine that regulates lymphocyte proliferation and peripheral tolerance. IL-2 activates mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase, and signal transducer and activator of transcription (STAT) pathways and modulates expression of tar...

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Autors principals: Kovanen, Panu E., Bernard, Jérôme, Al-Shami, Amin, Liu, Chengyu, Bollenbacher-Reilley, Julie, Young, Lynn, Pise-Masison, Cynthia, Spolski, Rosanne, Leonard, Warren J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Mechanisms of Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427334/
https://ncbi.nlm.nih.gov/pubmed/18430737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709887200
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