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Prediction of structural stability of short beta-hairpin peptides by molecular dynamics and knowledge-based potentials

BACKGROUND: The structural stability of peptides in solution strongly affects their binding affinities and specificities. Thus, in peptide biotechnology, an increase in the structural stability is often desirable. The present work combines two orthogonal computational techniques, Molecular Dynamics...

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Autori principali: Noy, Karin, Kalisman, Nir, Keasar, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427033/
https://ncbi.nlm.nih.gov/pubmed/18510728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-27
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