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Mechanical unfolding of a beta-hairpin using molecular dynamics.

Single-molecule mechanical unfolding experiments have the potential to provide insights into the details of protein folding pathways. To investigate the relationship between force-extension unfolding curves and microscopic events, we performed molecular dynamics simulations of the mechanical unfoldi...

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Autores principales: Bryant, Z, Pande, V S, Rokhsar, D S
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300663/
https://ncbi.nlm.nih.gov/pubmed/10653773
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