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Molecular mechanism and structure of Trigger Factor bound to the translating ribosome

Ribosome-associated chaperone Trigger Factor (TF) initiates folding of newly synthesized proteins in bacteria. Here, we pinpoint by site-specific crosslinking the sequence of molecular interactions of Escherichia coli TF and nascent chains during translation. Furthermore, we provide the first full-l...

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Detalhes bibliográficos
Main Authors: Merz, Frieder, Boehringer, Daniel, Schaffitzel, Christiane, Preissler, Steffen, Hoffmann, Anja, Maier, Timm, Rutkowska, Anna, Lozza, Jasmin, Ban, Nenad, Bukau, Bernd, Deuerling, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426727/
https://ncbi.nlm.nih.gov/pubmed/18497744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.89
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