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Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells
We observed that treatment of prostate cancer cells for 24 h with wogonin, a naturally occurring monoflavonoid, induced cell death in a dose- and time-dependent manner. Exposure of wogonin to LNCaP cells was associated with increased intracellular levels of p21(Cip-1), p27(Kip-1), p53, and PUMA, oli...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424318/ https://ncbi.nlm.nih.gov/pubmed/18377871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.02.023 |
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