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Network-based global inference of human disease genes

Deciphering the genetic basis of human diseases is an important goal of biomedical research. On the basis of the assumption that phenotypically similar diseases are caused by functionally related genes, we propose a computational framework that integrates human protein–protein interactions, disease...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Xuebing, Jiang, Rui, Zhang, Michael Q, Li, Shao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424293/
https://ncbi.nlm.nih.gov/pubmed/18463613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.27
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