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Network-based global inference of human disease genes

Deciphering the genetic basis of human diseases is an important goal of biomedical research. On the basis of the assumption that phenotypically similar diseases are caused by functionally related genes, we propose a computational framework that integrates human protein–protein interactions, disease...

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Detalhes bibliográficos
Main Authors: Wu, Xuebing, Jiang, Rui, Zhang, Michael Q, Li, Shao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424293/
https://ncbi.nlm.nih.gov/pubmed/18463613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.27
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