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Network-based global inference of human disease genes

Deciphering the genetic basis of human diseases is an important goal of biomedical research. On the basis of the assumption that phenotypically similar diseases are caused by functionally related genes, we propose a computational framework that integrates human protein–protein interactions, disease...

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Autors principals: Wu, Xuebing, Jiang, Rui, Zhang, Michael Q, Li, Shao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424293/
https://ncbi.nlm.nih.gov/pubmed/18463613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.27
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