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Network-based global inference of human disease genes

Deciphering the genetic basis of human diseases is an important goal of biomedical research. On the basis of the assumption that phenotypically similar diseases are caused by functionally related genes, we propose a computational framework that integrates human protein–protein interactions, disease...

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Autori principali: Wu, Xuebing, Jiang, Rui, Zhang, Michael Q, Li, Shao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424293/
https://ncbi.nlm.nih.gov/pubmed/18463613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.27
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