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Synthesis and Analysis of Oligonucleotides Containing Abasic Site Analogues
DNA damage results in the formation of abasic sites from the formal hydrolysis of the glycosidic bond (AP) and several oxidized abasic lesions. Previous studies on AP sites revealed that DNA polymerases preferentially incorporated dA opposite them in ~80% of the replication events in Escherichia col...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424248/ https://ncbi.nlm.nih.gov/pubmed/18324835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo702614p |
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