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Synthesis and Analysis of Oligonucleotides Containing Abasic Site Analogues

DNA damage results in the formation of abasic sites from the formal hydrolysis of the glycosidic bond (AP) and several oxidized abasic lesions. Previous studies on AP sites revealed that DNA polymerases preferentially incorporated dA opposite them in ~80% of the replication events in Escherichia col...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huang, Haidong, Greenberg, Marc M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424248/
https://ncbi.nlm.nih.gov/pubmed/18324835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo702614p
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