Dysregulation of TGF-β signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease

We previously demonstrated that CD4(+)CD25(+) T regulatory cells (Tregs), important for the maintenance of immune tolerance and prevention of autoimmune disease, from patients with human T lymphotropic virus type I (HTLV-I)–associated myelopathy/tropical spastic paraparesis (HAM/TSP) exhibit reduced...

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Detalhes bibliográficos
Main Authors: Grant, Christian, Oh, Unsong, Yao, Karen, Yamano, Yoshihisa, Jacobson, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424157/
https://ncbi.nlm.nih.gov/pubmed/18326816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-123430
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