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Identification and Synthesis of a Unique Thiocarbazate Cathepsin L Inhibitor
Library samples containing 2,5-disubstituted oxadiazoles were identified as potent hits in a high throughput screen (HTS) of the NIH Molecular Libraries Small Molecule Repository (MLSMR) directed at discovering inhibitors of cathepsin L. However, when synthesized in pure form, the putative actives w...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423727/ https://ncbi.nlm.nih.gov/pubmed/18060772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.10.107 |
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