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Identification and Synthesis of a Unique Thiocarbazate Cathepsin L Inhibitor
Library samples containing 2,5-disubstituted oxadiazoles were identified as potent hits in a high throughput screen (HTS) of the NIH Molecular Libraries Small Molecule Repository (MLSMR) directed at discovering inhibitors of cathepsin L. However, when synthesized in pure form, the putative actives w...
Gorde:
Egile Nagusiak: | , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
2007
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423727/ https://ncbi.nlm.nih.gov/pubmed/18060772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.10.107 |
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