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Identification and Synthesis of a Unique Thiocarbazate Cathepsin L Inhibitor

Library samples containing 2,5-disubstituted oxadiazoles were identified as potent hits in a high throughput screen (HTS) of the NIH Molecular Libraries Small Molecule Repository (MLSMR) directed at discovering inhibitors of cathepsin L. However, when synthesized in pure form, the putative actives w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Myers, Michael C., Shah, Parag P., Diamond, Scott L., Huryn, Donna M., Smith, Amos B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423727/
https://ncbi.nlm.nih.gov/pubmed/18060772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.10.107
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