Directed Evolution Generates a Novel Oncolytic Virus for the Treatment of Colon Cancer

BACKGROUND: Viral-mediated oncolysis is a novel cancer therapeutic approach with the potential to be more effective and less toxic than current therapies due to the agents selective growth and amplification in tumor cells. To date, these agents have been highly safe in patients but have generally fa...

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Główni autorzy: Kuhn, Irene, Harden, Paul, Bauzon, Maxine, Chartier, Cecile, Nye, Julie, Thorne, Steve, Reid, Tony, Ni, Shaoheng, Lieber, Andre, Fisher, Kerry, Seymour, Len, Rubanyi, Gabor M., Harkins, Richard N., Hermiston, Terry W.
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2008
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423470/
https://ncbi.nlm.nih.gov/pubmed/18560559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002409
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