Directed Evolution Generates a Novel Oncolytic Virus for the Treatment of Colon Cancer

BACKGROUND: Viral-mediated oncolysis is a novel cancer therapeutic approach with the potential to be more effective and less toxic than current therapies due to the agents selective growth and amplification in tumor cells. To date, these agents have been highly safe in patients but have generally fa...

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Bibliographic Details
Main Authors: Kuhn, Irene, Harden, Paul, Bauzon, Maxine, Chartier, Cecile, Nye, Julie, Thorne, Steve, Reid, Tony, Ni, Shaoheng, Lieber, Andre, Fisher, Kerry, Seymour, Len, Rubanyi, Gabor M., Harkins, Richard N., Hermiston, Terry W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423470/
https://ncbi.nlm.nih.gov/pubmed/18560559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002409
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