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Oncolytic Viruses: The Power of Directed Evolution

Attempts at developing oncolytic viruses have been primarily based on rational design. However, this approach has been met with limited success. An alternative approach employs directed evolution as a means of producing highly selective and potent anticancer viruses. In this method, diverse viruses...

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Autori principali: Bauzon, Maxine, Hermiston, Terry W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265225/
https://ncbi.nlm.nih.gov/pubmed/22312363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/586389
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