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Enhancer Blocking Activity of the Insulator at H19-ICR Is Independent of Chromatin Barrier Establishment
Transcriptional insulators are cis regulatory elements that organize chromatin into independently regulated domains. At the imprinted murine Igf2/H19 locus, the H19-ICR insulator prevents the activation of the Igf2 promoter on the maternal allele by enhancers that activate H19 on the same chromosome...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423287/ https://ncbi.nlm.nih.gov/pubmed/18378700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00091-08 |
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