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Analysis of the H19ICR Insulator

Transcriptional insulators are specialized cis-acting elements that protect promoters from inappropriate activation by distal enhancers. The H19 imprinting control region (ICR) functions as a CTCF-dependent, methylation-sensitive transcriptional insulator. We analyzed several insertional mutations a...

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Detalhes bibliográficos
Principais autores: Yoon, Young Soo, Jeong, Sangkyun, Rong, Qi, Park, Kye-Yoon, Chung, Jae Hoon, Pfeifer, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899958/
https://ncbi.nlm.nih.gov/pubmed/17339341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02170-06
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